Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy
Selective irreversible inhibitors of selenoprotein TXNRD1 yield anticancer efficacy without overt systemic toxicity in mouse models.
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Main Authors: | , , , , , , , , , , , , , , , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
2018
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在线阅读: | https://doi.org/10.1126/scitranslmed.aaf7444 |
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