Characterization of Hydrophilic Gold(I) N-Heterocyclic Carbene (NHC) Complexes as Potent TrxR Inhibitors Using Biochemical and Mass Spectrometric Approaches

We report here on the synthesis of a series of mono- and dinuclear gold(I) complexes exhibiting sulfonated bis(NHC) ligands and novel hydroxylated mono(NHC) Au(I) compounds, which were also examined for their biological activities. Initial cell viability assays show strong antiproliferative activiti...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Özden Karaca, Valeria Scalcon, Samuel M. Meier, Riccardo Bonsignore, J. Brouwer, Federica Tonolo, Alessandra Folda, Maria Pia Rigobello, Fritz E. Kühn, Angela Casini
स्वरूप: Artigo
भाषा:अंग्रेज़ी
प्रकाशित: 2017
ऑनलाइन पहुंच:https://doi.org/10.1021/acs.inorgchem.7b02345
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