Treg-specific IL-27Rα deletion uncovers a key role for IL-27 in Treg function to control autoimmunity

Treg-specific IL-27Rα deletion uncovers a key role for IL-27 in Treg function to control autoimmunity

Significance Interleukin-27 (IL-27) can promote or antagonize inflammatory responses. However, the cellular mechanisms underlying such highly diverse roles remain unclear. It was proposed that IL-27 exerts antiinflammatory functions by directly acting on conventional CD4 T cells to induce IL-10–prod...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jeong‐su Do, Dongkyun Kim, Sohee Kim, Alice Valentin-Torres, Nina Dvorina, Eunjung Jang, Vivekananthan Nagarajavel, Tara M. DeSilva, Xiaoxia Li, Angela H. Ting, Dario A.A. Vignali, Stephen A. Stohlman, William M. Baldwin, Booki Min
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 2017
Mynediad Ar-lein:https://doi.org/10.1073/pnas.1703100114
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Rhyngrwyd

https://doi.org/10.1073/pnas.1703100114

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