IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade
Programmed death-1–directed (PD-1–directed) immune checkpoint blockade results in durable antitumor activity in many advanced malignancies. Recent studies suggest that IFN-γ is a critical driver of programmed death ligand-1 (PD-L1) expression in cancer and host cells, and baseline intratumoral T cel...
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| Hauptverfasser: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Englisch |
| Veröffentlicht: |
2017
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| Online-Zugang: | https://doi.org/10.1172/jci91190 http://www.jci.org/articles/view/91190/files/pdf |
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