First-line panitumumab plus FOLFOX4 or FOLFIRI in colorectal cancer with multiple or unresectable liver metastases: A randomised, phase II trial (PLANET-TTD)

First-line panitumumab plus FOLFOX4 or FOLFIRI in colorectal cancer with multiple or unresectable liver metastases: A randomised, phase II trial (PLANET-TTD)

BackgroundIn first-line wild-type (WT)-Kirsten rat sarcoma viral oncogene homologue (KRAS) metastatic colorectal cancer (mCRC), panitumumab (Pmab) improves outcomes when added to FOLFOX [folinic acid, 5-fluorouracil, and oxaliplatin] or FOLFIRI [folinic acid, 5-fluorouracil, and irinotecan]. However...

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Main Authors: Alfredo Carrato, Albert Abad, Bartomeu Massutí, Cristina Grávalos, P. Escudero, Federico Longo-Muñoz, José-Luís Manzano, Auxiliadora Gómez, María José Safont, Javier Gállego, Beatriz García-Paredes, Carles Pericay, Rosario Dueñas, Fernando Rivera, Ferrán Losa, Manuel Valladares‐Ayerbes, Encarnación González‐Flores, Enrique Aranda
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Acesso em linha:https://doi.org/10.1016/j.ejca.2017.04.024
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https://doi.org/10.1016/j.ejca.2017.04.024

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