Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells

Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells

Group3 medulloblastoma (MBG3) that predominantly occur in young children are usually associated with MYC amplification and/or overexpression, frequent metastasis and a dismal prognosis. Physiologically relevant MBG3 models are currently lacking, making inferences related to their cellular origin thu...

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Main Authors: Daisuke Kawauchi, Robert J. Ogg, Liang-Tseng Liu, David Shih, David Finkelstein, Brian L. Murphy, Jerold E. Rehg, Andrey Korshunov, Christopher Calabrese, Frédérique Zindy, Timothy N. Phoenix, Yoshiya Kawaguchi, Jan Gronych, Richard J. Gilbertson, Peter Lichter, Amar Gajjar, Marcel Kool, Paul A. Northcott, Stefan M. Pfister, Martine F. Roussel
Format: Artigo
Language:English
Published: 2017
Online Access:https://doi.org/10.1038/onc.2017.110
https://www.nature.com/articles/onc2017110.pdf
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https://doi.org/10.1038/onc.2017.110
https://www.nature.com/articles/onc2017110.pdf

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