IRF8 is the target of SIRT1 for the inflammation response in macrophages
The type III histone deacetylase SIRT1 has recently emerged as a critical immune regulator by suppressing T-cell immunity and macrophage activation during inflammation, but its mechanism in regulating inflammatory response in macrophages remains unclear. Here we show that the expression of SIRT1 in...
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Main Authors: | , , , , , , , , , , , , |
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Format: | Artigo |
Language: | English |
Published: |
2016
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Online Access: | https://doi.org/10.1177/1753425916683751 |
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