IRF8 is the target of SIRT1 for the inflammation response in macrophages

The type III histone deacetylase SIRT1 has recently emerged as a critical immune regulator by suppressing T-cell immunity and macrophage activation during inflammation, but its mechanism in regulating inflammatory response in macrophages remains unclear. Here we show that the expression of SIRT1 in...

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Bibliographic Details
Main Authors: Yanhui Jia, Shichao Han, Jun Li, Hongtao Wang, Jiaqi Liu, Na Li, Xuekang Yang, Jihong Shi, Juntao Han, Yan Li, Xiaozhi Bai, Linlin Su, Dahai Hu
Format: Artigo
Language:English
Published: 2016
Online Access:https://doi.org/10.1177/1753425916683751
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