Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells
Glycolytic enzymes are known to play pivotal roles in cancer cell survival, yet their molecular mechanisms remain poorly understood. Phosphoglycerate mutase 1 (PGAM1) is an important glycolytic enzyme that coordinates glycolysis, pentose phosphate pathway, and serine biosynthesis in cancer cells. He...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2017
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| Online Access: | https://doi.org/10.1083/jcb.201607008 https://rupress.org/jcb/article-pdf/216/2/409/1403746/jcb_201607008.pdf |
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