Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells

Glycolytic enzymes are known to play pivotal roles in cancer cell survival, yet their molecular mechanisms remain poorly understood. Phosphoglycerate mutase 1 (PGAM1) is an important glycolytic enzyme that coordinates glycolysis, pentose phosphate pathway, and serine biosynthesis in cancer cells. He...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Jia Qu, Wenyi Sun, Jie Zhong, Hao Lv, Mingrui Zhu, Jun Xu, Nan Jin, Zuoquan Xie, Minjia Tan, Shuhai Lin, Meiyu Geng, Jian Ding, Min Huang
Hōputu: Artigo
Reo:Ingarihi
I whakaputaina: 2017
Urunga tuihono:https://doi.org/10.1083/jcb.201607008
https://rupress.org/jcb/article-pdf/216/2/409/1403746/jcb_201607008.pdf
Ngā Tūtohu: Tāpirihia he Tūtohu
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!