A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK/PI3K induced malignant growth
Somatic mutations activating MAPK/PI3K signalling play a pivotal role in both tumours and brain developmental disorders. We developed a zebrafish model of brain tumour based on somatic expression of oncogenes that activate MAPK/PI3K signalling in neural progenitor cells. HRASV12 was the most effecti...
Saved in:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | engelsk |
| Udgivet: |
2016
|
| Online adgang: | https://doi.org/10.1242/dmm.026500 http://dmm.biologists.org/content/dmm/10/1/15.full.pdf |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|