Comparison of exome-based HLA class I genotyping tools: identification of platform-specific genotyping errors

Accurate human leukocyte antigen (HLA) genotyping is critical in studies involving the immune system. Several algorithms to estimate HLA genotypes from whole-exome data were developed. We compared the accuracy of seven algorithms, including Optitype, Polysolver and PHLAT, as well as investigated pat...

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Hauptverfasser: Kazuma Kiyotani, Tu H, Yusuke Nakamura
Format: Artigo
Sprache:Englisch
Veröffentlicht: 2016
Online-Zugang:https://doi.org/10.1038/jhg.2016.141
https://www.nature.com/articles/jhg2016141.pdf
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