A Cinnamon-Derived Procyanidin Compound Displays Anti-HIV-1 Activity by Blocking Heparan Sulfate- and Co-Receptor- Binding Sites on gp120 and Reverses T Cell Exhaustion via Impeding Tim-3 and PD-1 Upregulation
Amongst the many strategies aiming at inhibiting HIV-1 infection, blocking viral entry has been recently recognized as a very promising approach. Using diverse in vitro models and a broad range of HIV-1 primary patient isolates, we report here that IND02, a type A procyanidin polyphenol extracted fr...
-д хадгалсан:
| Үндсэн зохиолчид: | , , , , , , , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | англи |
| Хэвлэсэн: |
2016
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| Онлайн хандалт: | https://doi.org/10.1371/journal.pone.0165386 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0165386&type=printable |
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