Dual action of neurokinin-1 antagonists on Mas-related GPCRs

The challenge of translating findings from animal models to the clinic is well known. An example of this challenge is the striking effectiveness of neurokinin-1 receptor (NK-1R) antagonists in mouse models of inflammation coupled with their equally striking failure in clinical investigations in huma...

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Príomhchruthaitheoirí: Ehsan Azimi, Vemuri B. Reddy, Kai-Ting Shade, Robert M. Anthony, Sébastien Talbot, Paula Juliana Seadi Pereira, Ethan A. Lerner
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 2016
Rochtain ar líne:https://doi.org/10.1172/jci.insight.89362
http://insight.jci.org/articles/view/89362/files/pdf
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