Exposure to human immunodeficiency virus/hepatitis C virus in hepatic and stellate cell lines reveals cooperative profibrotic transcriptional activation between viruses and cell types

Exposure to human immunodeficiency virus/hepatitis C virus in hepatic and stellate cell lines reveals cooperative profibrotic transcriptional activation between viruses and cell types

Human immunodeficiency virus (HIV)/hepatitis C virus (HCV) coinfection accelerates progressive liver fibrosis; however, the mechanisms remain poorly understood. HCV and HIV independently induce profibrogenic markers transforming growth factor beta-1 (TGFβ1) (mediated by reactive oxygen species [ROS]...

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Hlavní autoři: Shadi Salloum, Jacinta A. Holmes, Rohit Jindal, Shyam Sundhar Bale, Cynthia Brisac, Nadia Alatrakchi, Anna Lidofsky, Annie J. Kruger, Dahlene N. Fusco, Jay Luther, Esperance Schaefer, Wenyu Lin, Martin L. Yarmush, Raymond T. Chung
Médium: Artigo
Jazyk:angličtina
Vydáno: 2016
On-line přístup:https://doi.org/10.1002/hep.28766
https://aasldpubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.28766
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https://doi.org/10.1002/hep.28766
https://aasldpubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.28766

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