Exposure to human immunodeficiency virus/hepatitis C virus in hepatic and stellate cell lines reveals cooperative profibrotic transcriptional activation between viruses and cell types

Exposure to human immunodeficiency virus/hepatitis C virus in hepatic and stellate cell lines reveals cooperative profibrotic transcriptional activation between viruses and cell types

Human immunodeficiency virus (HIV)/hepatitis C virus (HCV) coinfection accelerates progressive liver fibrosis; however, the mechanisms remain poorly understood. HCV and HIV independently induce profibrogenic markers transforming growth factor beta-1 (TGFβ1) (mediated by reactive oxygen species [ROS]...

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Hoofdauteurs: Shadi Salloum, Jacinta A. Holmes, Rohit Jindal, Shyam Sundhar Bale, Cynthia Brisac, Nadia Alatrakchi, Anna Lidofsky, Annie J. Kruger, Dahlene N. Fusco, Jay Luther, Esperance Schaefer, Wenyu Lin, Martin L. Yarmush, Raymond T. Chung
Formaat: Artigo
Taal:Engels
Gepubliceerd in: 2016
Online toegang:https://doi.org/10.1002/hep.28766
https://aasldpubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.28766
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https://doi.org/10.1002/hep.28766
https://aasldpubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.28766

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