A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC

Abstract Colorectal cancer (CRC) is a highly heterogeneous disease, for which prognosis has been relegated to clinicopathologic staging for decades. There is a need to stratify subpopulations of CRC on a molecular basis to better predict outcome and assign therapies. Here we report targeted exome-se...

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Bibliografiske detaljer
Main Authors: Michael J. Schell, Mingli Yang, Jamie K. Teer, Fang Yin Lo, Anup Madan, Domenico Coppola, Álvaro N.A. Monteiro, Michael Nebozhyn, Binglin Yue, Andrey Loboda, Gabriel A. Bien‐Willner, Danielle M. Greenawalt, Timothy J. Yeatman
Format: Artigo
Sprog:engelsk
Udgivet: 2016
Online adgang:https://doi.org/10.1038/ncomms11743
https://www.nature.com/articles/ncomms11743.pdf
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