A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC
Abstract Colorectal cancer (CRC) is a highly heterogeneous disease, for which prognosis has been relegated to clinicopathologic staging for decades. There is a need to stratify subpopulations of CRC on a molecular basis to better predict outcome and assign therapies. Here we report targeted exome-se...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2016
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| Online Access: | https://doi.org/10.1038/ncomms11743 https://www.nature.com/articles/ncomms11743.pdf |
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