A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC

Abstract Colorectal cancer (CRC) is a highly heterogeneous disease, for which prognosis has been relegated to clinicopathologic staging for decades. There is a need to stratify subpopulations of CRC on a molecular basis to better predict outcome and assign therapies. Here we report targeted exome-se...

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Autores principales: Michael J. Schell, Mingli Yang, Jamie K. Teer, Fang Yin Lo, Anup Madan, Domenico Coppola, Álvaro N.A. Monteiro, Michael Nebozhyn, Binglin Yue, Andrey Loboda, Gabriel A. Bien‐Willner, Danielle M. Greenawalt, Timothy J. Yeatman
Formato: Artigo
Lenguaje:inglés
Publicado: 2016
Acceso en línea:https://doi.org/10.1038/ncomms11743
https://www.nature.com/articles/ncomms11743.pdf
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