A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC

Abstract Colorectal cancer (CRC) is a highly heterogeneous disease, for which prognosis has been relegated to clinicopathologic staging for decades. There is a need to stratify subpopulations of CRC on a molecular basis to better predict outcome and assign therapies. Here we report targeted exome-se...

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Hlavní autoři: Michael J. Schell, Mingli Yang, Jamie K. Teer, Fang Yin Lo, Anup Madan, Domenico Coppola, Álvaro N.A. Monteiro, Michael Nebozhyn, Binglin Yue, Andrey Loboda, Gabriel A. Bien‐Willner, Danielle M. Greenawalt, Timothy J. Yeatman
Médium: Artigo
Jazyk:angličtina
Vydáno: 2016
On-line přístup:https://doi.org/10.1038/ncomms11743
https://www.nature.com/articles/ncomms11743.pdf
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