TRPV4 Regulates Breast Cancer Cell Extravasation, Stiffness and Actin Cortex

Abstract Metastasis is a significant health issue. The standard mode of care is combination of chemotherapy and targeted therapeutics but the 5-year survival rate remains low. New/better drug targets that can improve outcomes of patients with metastatic disease are needed. Metastasis is a complex pr...

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Bibliographische Detailangaben
Hauptverfasser: Wen Hsin Lee, Lee Yee Choong, Naing Naing Mon, Ssu-Yi Lu, Qingsong Lin, Brendan Pang, Benedict Yan, Sri Ram Krishna Vedula, Himanshu Singh, Tuan Zea Tan, Jean Paul Thiery, Chwee Teck Lim, Patrick Boon Ooi Tan, Martin Johansson, Christian Harteneck, Yoon Pin Lim
Format: Artigo
Sprache:Englisch
Veröffentlicht: 2016
Online-Zugang:https://doi.org/10.1038/srep27903
https://www.nature.com/articles/srep27903.pdf
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