The legacy of the F344 rat as a cancer bioassay model (a retrospective summary of three common F344 rat neoplasms)
The Fischer 344 (F344) rat was used by the National Toxicology Program (NTP) for over 5 decades for toxicity and carcinogenicity studies. However, in 2006, the NTP decided to switch to a different rat stock due largely to high background control incidences of Leydig cell tumors (LCTs) and mononuclea...
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| Główni autorzy: | , , , |
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| Format: | Revisão |
| Język: | angielski |
| Wydane: |
2016
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| Dostęp online: | https://doi.org/10.1080/10408444.2016.1174669 https://www.tandfonline.com/doi/pdf/10.1080/10408444.2016.1174669?needAccess=true |
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