The legacy of the F344 rat as a cancer bioassay model (a retrospective summary of three common F344 rat neoplasms)

The Fischer 344 (F344) rat was used by the National Toxicology Program (NTP) for over 5 decades for toxicity and carcinogenicity studies. However, in 2006, the NTP decided to switch to a different rat stock due largely to high background control incidences of Leydig cell tumors (LCTs) and mononuclea...

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Détails bibliographiques
Auteurs principaux: Robert R. Maronpot, Abraham Nyska, Jennifer E. Foreman, Yuval Ramot
Format: Revisão
Langue:anglais
Publié: 2016
Accès en ligne:https://doi.org/10.1080/10408444.2016.1174669
https://www.tandfonline.com/doi/pdf/10.1080/10408444.2016.1174669?needAccess=true
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