Stoichiometry for α-bungarotoxin block of α7 acetylcholine receptors
Abstract α-Bungarotoxin (α-Btx) binds to the five agonist binding sites on the homopentameric α7-acetylcholine receptor, yet the number of bound α-Btx molecules required to prevent agonist-induced channel opening remains unknown. To determine the stoichiometry for α-Btx blockade, we generate recepto...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | angleščina |
| Izdano: |
2015
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| Online dostop: | https://doi.org/10.1038/ncomms9057 https://www.nature.com/articles/ncomms9057.pdf |
| Oznake: |
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