A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder

A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder

Genome-wide association studies (GWASs) of major depressive disorder (MDD) have identified few significant associations. Testing the aggregation of genetic variants, in particular biological pathways, may be more powerful. Regional heritability analysis can be used to detect genomic regions that con...

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Main Authors: Yanni Zeng, Pau Navarro, Ana Maria Fernandez-Pujals, Lynsey S. Hall, Toni‐Kim Clarke, Pippa A. Thomson, Blair H. Smith, Lynne J. Hocking, Sandosh Padmanabhan, Caroline Hayward, Donald J. MacIntyre, Naomi R. Wray, Ian J. Deary, David J. Porteous, Chris Haley, Andrew M. McIntosh
Format: Artigo
Language:English
Published: 2016
Online Access:https://doi.org/10.1016/j.biopsych.2016.04.017
http://www.biologicalpsychiatryjournal.com/article/S0006322316323320/pdf
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https://doi.org/10.1016/j.biopsych.2016.04.017
http://www.biologicalpsychiatryjournal.com/article/S0006322316323320/pdf

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