HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death
Abstract Necroptosis is a caspase-independent form of regulated cell death that has been implicated in the development of a range of inflammatory, autoimmune and neurodegenerative diseases. The pseudokinase, Mixed Lineage Kinase Domain-Like (MLKL), is the most terminal known obligatory effector in t...
Zapisane w:
| Główni autorzy: | , , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Język: | angielski |
| Wydane: |
2016
|
| Dostęp online: | https://doi.org/10.1038/cddis.2015.386 https://www.nature.com/articles/cddis2015386.pdf |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|