Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan

Increased production of reactive oxygen species (ROS) has long been considered a cause of aging. However, recent studies have implicated ROS as essential secondary messengers. Here we show that the site of ROS production significantly contributes to their apparent dual nature. We report that ROS inc...

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Main Authors: Filippo Scialò, Ashwin Sriram, Daniel J.M. Fernández‐Ayala, Nina Gubina, Madis Lõhmus, Glyn Nelson, Angela Logan, Helen Cooper, Plácido Navas, José Antonio Enrı́quez, Michael P. Murphy, Alberto Sanz
格式: Artigo
語言:英语
出版: 2016
在線閱讀:https://doi.org/10.1016/j.cmet.2016.03.009
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