Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan

Increased production of reactive oxygen species (ROS) has long been considered a cause of aging. However, recent studies have implicated ROS as essential secondary messengers. Here we show that the site of ROS production significantly contributes to their apparent dual nature. We report that ROS inc...

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Autori principali: Filippo Scialò, Ashwin Sriram, Daniel J.M. Fernández‐Ayala, Nina Gubina, Madis Lõhmus, Glyn Nelson, Angela Logan, Helen Cooper, Plácido Navas, José Antonio Enrı́quez, Michael P. Murphy, Alberto Sanz
Natura: Artigo
Lingua:inglese
Pubblicazione: 2016
Accesso online:https://doi.org/10.1016/j.cmet.2016.03.009
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