Prion Strain Differences in Accumulation of PrPSc on Neurons and Glia Are Associated with Similar Expression Profiles of Neuroinflammatory Genes: Comparison of Three Prion Strains
Misfolding and aggregation of host proteins are important features of the pathogenesis of neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, frontotemporal dementia and prion diseases. In all these diseases, the misfolded protein increases in amount by a mechani...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | engelsk |
| Udgivet: |
2016
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| Online adgang: | https://doi.org/10.1371/journal.ppat.1005551 https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005551&type=printable |
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