Riluzole exerts central and peripheral modulating effects in amyotrophic lateral sclerosis
Riluzole, a benzothiazole derivative, has been shown to be effective in prolonging survival in amyotrophic lateral sclerosis. The mechanisms by which riluzole exerts neuroprotective effects in amyotrophic lateral sclerosis remains to be fully elucidated, although inhibition of glutamatergic transmis...
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Auteurs principaux: | , , , , , , |
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Format: | Artigo |
Langue: | anglais |
Publié: |
2013
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Accès en ligne: | https://doi.org/10.1093/brain/awt085 https://academic.oup.com/brain/article-pdf/136/5/1361/11139607/awt085.pdf |
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