Riluzole exerts central and peripheral modulating effects in amyotrophic lateral sclerosis

Riluzole, a benzothiazole derivative, has been shown to be effective in prolonging survival in amyotrophic lateral sclerosis. The mechanisms by which riluzole exerts neuroprotective effects in amyotrophic lateral sclerosis remains to be fully elucidated, although inhibition of glutamatergic transmis...

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Auteurs principaux: Steve Vucic, Cindy Lin, Benjamin C. Cheah, Jenna Murray, Parvathi Menon, Arun V. Krishnan, Matthew C. Kiernan
Format: Artigo
Langue:anglais
Publié: 2013
Accès en ligne:https://doi.org/10.1093/brain/awt085
https://academic.oup.com/brain/article-pdf/136/5/1361/11139607/awt085.pdf
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