Plasma Membrane Repair Is Regulated Extracellularly by Proteases Released from Lysosomes

Eukaryotic cells rapidly repair wounds on their plasma membrane. Resealing is Ca2+-dependent, and involves exocytosis of lysosomes followed by massive endocytosis. Extracellular activity of the lysosomal enzyme acid sphingomyelinase was previously shown to promote endocytosis and wound removal. Howe...

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Main Authors: Thiago Castro‐Gomes, Matthias Corrotte, Christina Tam, Norma W. Andrews
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Acesso em linha:https://doi.org/10.1371/journal.pone.0152583
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0152583&type=printable
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