Plasma Membrane Repair Is Regulated Extracellularly by Proteases Released from Lysosomes
Eukaryotic cells rapidly repair wounds on their plasma membrane. Resealing is Ca2+-dependent, and involves exocytosis of lysosomes followed by massive endocytosis. Extracellular activity of the lysosomal enzyme acid sphingomyelinase was previously shown to promote endocytosis and wound removal. Howe...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Acesso em linha: | https://doi.org/10.1371/journal.pone.0152583 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0152583&type=printable |
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