Opportunities for immunotherapy in microsatellite instable colorectal cancer
Microsatellite instability (MSI), the somatic accumulation of length variations in repetitive DNA sequences called microsatellites, is frequently observed in both hereditary and sporadic colorectal cancer (CRC). It has been established that defects in the DNA mismatch repair (MMR) pathway underlie t...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Revisão |
| Jazyk: | angličtina |
| Vydáno: |
2016
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| On-line přístup: | https://doi.org/10.1007/s00262-016-1832-7 https://link.springer.com/content/pdf/10.1007%2Fs00262-016-1832-7.pdf |
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