Opportunities for immunotherapy in microsatellite instable colorectal cancer

Microsatellite instability (MSI), the somatic accumulation of length variations in repetitive DNA sequences called microsatellites, is frequently observed in both hereditary and sporadic colorectal cancer (CRC). It has been established that defects in the DNA mismatch repair (MMR) pathway underlie t...

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Bibliografske podrobnosti
Main Authors: Harm Westdorp, Felix L. Fennemann, Robbert D.A. Weren, Tanya M. Bisseling, Marjolijn J. L. Ligtenberg, Carl G. Figdor, Gerty Schreibelt, Nicoline Hoogerbrugge, Florian Wimmers, I. Jolanda M. de Vries
Format: Revisão
Jezik:angleščina
Izdano: 2016
Online dostop:https://doi.org/10.1007/s00262-016-1832-7
https://link.springer.com/content/pdf/10.1007%2Fs00262-016-1832-7.pdf
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