Conditional deletion of <i>L1CAM</i> in human neurons impairs both axonal and dendritic arborization and action potential generation
Hundreds of L1CAM gene mutations have been shown to be associated with congenital hydrocephalus, severe intellectual disability, aphasia, and motor symptoms. How such mutations impair neuronal function, however, remains unclear. Here, we generated human embryonic stem (ES) cells carrying a condition...
Saved in:
| Main Authors: | , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
2016
|
| 在線閱讀: | https://doi.org/10.1084/jem.20150951 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|