Perinatal Lead Exposure Alters Gut Microbiota Composition and Results in Sex-specific Bodyweight Increases in Adult Mice

Heavy metal pollution is a principle source of environmental contamination. Epidemiological and animal data suggest that early life lead (Pb) exposure results in critical effects on epigenetic gene regulation and child and adult weight trajectories. Using a mouse model of human-relevant exposure, we...

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Main Authors: Jianfeng Wu, Xiaoquan Wen, Christopher Faulk, Kevin F. Boehnke, Huapeng Zhang, Dana C. Dolinoy, Chuanwu Xi
格式: Artigo
语言:英语
出版: 2016
在线阅读:https://doi.org/10.1093/toxsci/kfw046
https://academic.oup.com/toxsci/article-pdf/151/2/324/16689839/kfw046.pdf
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