ALK Protein Analysis by IHC Staining after Recent Regulatory Changes: A Comparison of Two Widely Used Approaches, Revision of the Literature, and a New Testing Algorithm

ALK Protein Analysis by IHC Staining after Recent Regulatory Changes: A Comparison of Two Widely Used Approaches, Revision of the Literature, and a New Testing Algorithm

IntroductionRecent regulatory changes have allowed the diagnostic use of immunohistochemical (IHC) analysis for the identification of patients with non–small cell lung cancer who are eligible for treatment with anaplastic lymphoma receptor tyrosine kinase (ALK) inhibitors. The U.S. Food and Drug Adm...

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Huvudupphovsmän: Antonio Marchetti, Alessia Di Lorito, Maria Vittoria Pace, Manuela Iezzi, Lara Felicioni, Tommaso D’Antuono, Giampaolo Filice, Luigi Guetti, Felice Mucilli, Fiamma Buttitta
Materialtyp: Artigo
Språk:engelska
Publicerad: 2016
Länkar:https://doi.org/10.1016/j.jtho.2015.12.111
http://www.jto.org/article/S1556086416003324/pdf
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https://doi.org/10.1016/j.jtho.2015.12.111
http://www.jto.org/article/S1556086416003324/pdf

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