Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling
The G protein-coupled receptor GHS-R1a mediates ghrelin-induced growth hormone secretion, food intake, and reward-seeking behaviors. GHS-R1a signals through Gq, Gi/o, G13, and arrestin. Biasing GHS-R1a signaling with specific ligands may lead to the development of more selective drugs to treat obesi...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Saesneg |
| Cyhoeddwyd: |
2015
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| Mynediad Ar-lein: | https://doi.org/10.1074/jbc.m115.659250 http://www.jbc.org/article/S0021925820494724/pdf |
| Tagiau: |
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