A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy
Background Depending on the epidemiological setting, a variable proportion of leprosy patients will suffer from excessive pro-inflammatory responses, termed type-1 reactions (T1R). The LRRK2 gene encodes a multi-functional protein that has been shown to modulate pro-inflammatory responses. Variants...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | anglais |
| Publié: |
2016
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| Accès en ligne: | https://doi.org/10.1371/journal.pntd.0004412 https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0004412&type=printable |
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