Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study

Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study

Background and Objective:Aberrant lipid metabolism has been implicated in sporadic Alzheimer's disease (AD). The current study investigated plasma phospholipid and sphingolipid profiles in individuals carrying PSEN1 mutations responsible for autosomal dominant AD (ADAD). Methods:Study participa...

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Hauptverfasser: Pratishtha Chatterjee, Wei Ling Florence Lim, Guanghou Shui, Veer Bala Gupta, Ian James, Anne M. Fagan, Chengjie Xiong, Hamid R. Sohrabi, Kevin Taddei, Belinda M. Brown, Tammie L.S. Benzinger, Colin L. Masters, Stuart G. Snowden, Marcus Wenk, Randall J. Bateman, John C. Morris, Ralph N. Martins
Format: Artigo
Sprache:Englisch
Veröffentlicht: 2016
Online-Zugang:https://doi.org/10.3233/jad-150948
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https://doi.org/10.3233/jad-150948

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