Bifunctional intercalation and sequence specificity in the binding of quinomycin and triostin antibiotics to deoxyribonucleic acid
Quinomycin C, triostin A and triostin C are peptide antibiotics of the quinoxaline family, of which echinomycin (quinomycin A) is also a member. They all remove and reverse the supercoiling of closed circular duplex DNA from bacteriophage PM2 in the fashion characteristic of intercalating drugs, and...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | English |
| Published: |
1978
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| Online Access: | https://doi.org/10.1042/bj1730115 |
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