EpCAM aptamer mediated cancer cell specific delivery of EpCAM siRNA using polymeric nanocomplex
Abstract Background Epithelial cell adhesion molecule (EpCAM) is overexpressed in solid tumors and regarded as a putative cancer stem cell marker. Here, we report that employing EpCAM aptamer (EpApt) and EpCAM siRNA (SiEp) dual approach, for the targeted delivery of siRNA to EpCAM positive cancer ce...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | angleščina |
| Izdano: |
2015
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| Online dostop: | https://doi.org/10.1186/s12929-014-0108-9 https://jbiomedsci.biomedcentral.com/counter/pdf/10.1186/s12929-014-0108-9 |
| Oznake: |
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