EpCAM aptamer mediated cancer cell specific delivery of EpCAM siRNA using polymeric nanocomplex

EpCAM aptamer mediated cancer cell specific delivery of EpCAM siRNA using polymeric nanocomplex

Abstract Background Epithelial cell adhesion molecule (EpCAM) is overexpressed in solid tumors and regarded as a putative cancer stem cell marker. Here, we report that employing EpCAM aptamer (EpApt) and EpCAM siRNA (SiEp) dual approach, for the targeted delivery of siRNA to EpCAM positive cancer ce...

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Detaylı Bibliyografya
Asıl Yazarlar: Nithya Subramanian, Jagat R. Kanwar, Prasanna kumar Athalya, Narayanan Janakiraman, Vikas Khetan, Sailaja Eluchuri, Subramanian Krishnakumar
Materyal Türü: Artigo
Dil:İngilizce
Baskı/Yayın Bilgisi: 2015
Online Erişim:https://doi.org/10.1186/s12929-014-0108-9
https://jbiomedsci.biomedcentral.com/counter/pdf/10.1186/s12929-014-0108-9
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https://doi.org/10.1186/s12929-014-0108-9
https://jbiomedsci.biomedcentral.com/counter/pdf/10.1186/s12929-014-0108-9

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