5′RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy

5′RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy

The transcriptome is subject to multiple changes during pathogenesis, including the use of alternate 5′ start-sites that can affect transcription levels and output. Current RNA sequencing techniques can assess mRNA levels, but do not robustly detect changes in 5′ start-site use. Here, we developed a...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Danos C. Christodoulou, Hiroko Wakimoto, Kenji Onoue, Seda Eminaga, Joshua M. Gorham, Steven R. DePalma, Daniel S. Herman, Polakit Teekakirikul, David A. Conner, David McKean, Andrea A. Domenighetti, Anton Aboukhalil, Stephen Chang, Gyan Srivastava, Barbara McDonough, Philip L. De Jager, Ju Chen, Martha L. Bulyk, Jochen D. Muehlschlegel, Christine E. Seidman, J G Seidman
Materyal Türü: Artigo
Dil:İngilizce
Baskı/Yayın Bilgisi: 2014
Online Erişim:https://doi.org/10.1172/jci70108
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Internet

https://doi.org/10.1172/jci70108

Benzer Materyaller