Visceral endoderm-restricted translation of <i>Otx1</i> mediates recovery of <i>Otx2</i> requirements for specification of anterior neural plate and normal gastrulation
ABSTRACT Otx1 and Otx2, two murine homologs of the Drosophila orthodenticle (otd) gene, contribute to brain morphogenesis. In particular Otx1 null mice are viable and show spontaneous epileptic seizures and abnormalities affecting the dorsal telencephalic cortex. Otx2 null mice die early in developm...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | English |
Published: |
1998
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Online Access: | https://doi.org/10.1242/dev.125.24.5091 https://journals.biologists.com/dev/article-pdf/125/24/5091/1131676/5091.pdf |
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