Visceral endoderm-restricted translation of <i>Otx1</i> mediates recovery of <i>Otx2</i> requirements for specification of anterior neural plate and normal gastrulation

ABSTRACT Otx1 and Otx2, two murine homologs of the Drosophila orthodenticle (otd) gene, contribute to brain morphogenesis. In particular Otx1 null mice are viable and show spontaneous epileptic seizures and abnormalities affecting the dorsal telencephalic cortex. Otx2 null mice die early in developm...

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Bibliographic Details
Main Authors: Dario Acampora, Virginia Avantaggiato, Francesca Tuorto, Paola Briata, Giorgio Corte, Antonio Simeone
Format: Artigo
Language:English
Published: 1998
Online Access:https://doi.org/10.1242/dev.125.24.5091
https://journals.biologists.com/dev/article-pdf/125/24/5091/1131676/5091.pdf
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