Desensitization of the insulin receptor at an early postreceptor step by prolonged exposure to antireceptor antibody
We have used an adipocyte-like cell line, the 3T3-L1 fatty fibroblasts, to compare acute and chronic effects of autoantibodies directed against the insulin receptor. Acute exposure of the cells in tissue culture to the antibodies resulted in a blockade of insulin binding and stimulation of 2-deoxy-g...
שמור ב:
| Main Authors: | , , , |
|---|---|
| פורמט: | Artigo |
| שפה: | אנגלית |
| יצא לאור: |
1979
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| גישה מקוונת: | https://doi.org/10.1073/pnas.76.2.809 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
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