Heterozygous LmnadelK32 mice develop dilated cardiomyopathy through a combined pathomechanism of haploinsufficiency and peptide toxicity

Heterozygous LmnadelK32 mice develop dilated cardiomyopathy through a combined pathomechanism of haploinsufficiency and peptide toxicity

Dilated cardiomyopathy (DCM) associates left ventricular (LV) dilatation and systolic dysfunction and is a major cause of heart failure and cardiac transplantation. LMNA gene encodes lamins A/C, proteins of the nuclear envelope. LMNA mutations cause DCM with conduction and/or rhythm defects. The pat...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Marie‐Elodie Cattin, A. Bertrand, Saskia Schlossarek, Marie‐Catherine Le Bihan, Søren Skov Jensen, Christiane Neuber, Claudia Crocini, Sophia Maron, Jeanne Lainé, Nathalie Mougenot, Shaïda Varnous, Yves Fromes, Arne Hansen, Thomas Eschenhagen, V. Decostre, Lucie Carrier, Gisèle Bonne
Format: Artigo
Jezik:engleski
Izdano: 2013
Online pristup:https://doi.org/10.1093/hmg/ddt172
https://academic.oup.com/hmg/article-pdf/22/15/3152/17260382/ddt172.pdf
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Internet

https://doi.org/10.1093/hmg/ddt172
https://academic.oup.com/hmg/article-pdf/22/15/3152/17260382/ddt172.pdf

Slični predmeti