Inhibition of Fibroblast Growth Factor 19 Reduces Tumor Growth by Modulating β-Catenin Signaling
Fibroblast growth factors (FGF) play important roles in development, angiogenesis, and cancer. FGF19 uniquely binds to FGF receptor 4 (FGFR4). Our previous study has shown that FGF19 transgenic tumors have an activated Wnt-pathway phenotype. Wnt signaling is implicated in initiating or promoting FGF...
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| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Language: | English |
| Published: |
2008
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| Online Access: | https://doi.org/10.1158/0008-5472.can-07-2325 https://aacrjournals.org/cancerres/article-pdf/68/13/5086/2594727/5086.pdf |
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