Downregulation of PPARγ by miR-548d-5p suppresses the adipogenic differentiation of human bone marrow mesenchymal stem cells and enhances their osteogenic potential
Human bone marrow mesenchymal stem cells (hBMSCs) are multipotent cells that can differentiate into a variety of cell types. Elevated expression of peroxisome proliferator-activated receptor-γ (PPARγ) promotes the adipogenic differentiation of hBMSCs, and reduces their osteogenic differentiation. Mi...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Englisch |
| Veröffentlicht: |
2014
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| Online-Zugang: | https://doi.org/10.1186/1479-5876-12-168 https://translational-medicine.biomedcentral.com/counter/pdf/10.1186/1479-5876-12-168 |
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