Anti-inflammatory lipoxin A <sub>4</sub> is an endogenous allosteric enhancer of CB <sub>1</sub> cannabinoid receptor

Anti-inflammatory lipoxin A <sub>4</sub> is an endogenous allosteric enhancer of CB <sub>1</sub> cannabinoid receptor

Allosteric modulation of G-protein–coupled receptors represents a key goal of current pharmacology. In particular, endogenous allosteric modulators might represent important targets of interventions aimed at maximizing therapeutic efficacy and reducing side effects of drugs. Here we show that the an...

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Bibliografski detalji
Glavni autori: Fabrício A. Pamplona, Juliano Ferreira, Octávio Menezes de Lima, Filipe Silveira Duarte, Allisson Freire Bento, Stefânia Forner, Jardel Gomes Villarinho, Luigi Bellocchio, Carsten T. Wotjak, Raissa Lerner, Krisztina Monory, Beat Lutz, Cláudio Canetti, Isabel Matias, João Β. Calixto, Giovanni Marsicano, Marília Zaluar P. Guimarães, Reinaldo Ν. Takahashi
Format: Artigo
Jezik:engleski
Izdano: 2012
Online pristup:https://doi.org/10.1073/pnas.1202906109
https://www.pnas.org/content/pnas/109/51/21134.full.pdf
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https://doi.org/10.1073/pnas.1202906109
https://www.pnas.org/content/pnas/109/51/21134.full.pdf

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