SIRT1 regulates tyrosine hydroxylase expression and differentiation of neuroblastoma cells via FOXO3a

SIRT1 regulates tyrosine hydroxylase expression and differentiation of neuroblastoma cells via FOXO3a

To examine the function of SIRT1 in neuronal differentiation, we employed all‐trans retinoic acid (ATRA)‐induced differentiation of neuroblastoma cells. Nicotinamide inhibited neurite outgrowth and tyrosine hydroxylase (TH) expression. Inhibition of PARP or histone deacetylase did not inhibit TH exp...

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Bibliografiske detaljer
Main Authors: Min-Ju Kim, Kyungsook Ahn, Seong‐Hoon Park, Hong-Jun Kang, Bong Geom Jang, Soo Jin Oh, Sun-Mee Oh, Yu‐Jin Jeong, Jee-In Heo, Jun‐Gyo Suh, Soon Sung Lim, Yoon-Jung Ko, Sung‐Oh Huh, Sung Chan Kim, Jae-Bong Park, Jaebong Kim, Jong‐Il Kim, Sangmee Ahn Jo, Jae‐Yong Lee
Format: Artigo
Sprog:engelsk
Udgivet: 2009
Online adgang:https://doi.org/10.1016/j.febslet.2009.03.007
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.febslet.2009.03.007
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Internet

https://doi.org/10.1016/j.febslet.2009.03.007
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.febslet.2009.03.007

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