SIRT1 regulates tyrosine hydroxylase expression and differentiation of neuroblastoma cells via FOXO3a
To examine the function of SIRT1 in neuronal differentiation, we employed all‐trans retinoic acid (ATRA)‐induced differentiation of neuroblastoma cells. Nicotinamide inhibited neurite outgrowth and tyrosine hydroxylase (TH) expression. Inhibition of PARP or histone deacetylase did not inhibit TH exp...
Kaydedildi:
Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | İngilizce |
Baskı/Yayın Bilgisi: |
2009
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Online Erişim: | https://doi.org/10.1016/j.febslet.2009.03.007 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.febslet.2009.03.007 |
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